RESUMO
La miastenia gravis es el trastorno más común dentro de las enfermedades que afectan a la transmisión neuromuscular. Actualmente es uno de los trastornos autoinmunes mejor definidos y entendidos. Esta se caracteriza por debilidad y fatiga de forma fluctuante y en combinación variable de los músculos oculares, funciones bulbares, de las extremidades y de los músculos respiratorios. Estos síntomas son el resultado de un ataque inmunológico contra la membrana postsináptica de la unión neuromuscular. El diagnóstico de la miastenia gravis depende tanto de pruebas clínicas como serológicas. Es una enfermedad que puede ser controlada de forma efectiva con las distintas líneas terapéuticas actuales, incluso logrando la remisión de esta. A continuación, presentamos una actualización de esta interesante enfermedad
Myasthenia gravis is one of the most common disorders that affect neuromuscular transmission. It is currently one of the most understood and characterised autoimmune disorders Its typical symptoms are fluctuating weakness and fatigue that affects a combination of ocular muscles, bulbar functions, as well as limb and respiratory muscles, which are due to an immune attack against the postsynaptic membrane of the neuromuscular junction. The diagnosis of myasthenia gravis is based on clinical and serological test. It is a disease that can be effectively controlled with the current therapeutic lines, even achieving a complete remission. An update of this interesting disorder is now presented
Assuntos
Humanos , Miastenia Gravis/fisiopatologia , Junção Neuromuscular/imunologia , Membranas Sinápticas/imunologia , Miastenia Gravis/diagnóstico , Miastenia Gravis/terapiaRESUMO
Myasthenia gravis is one of the most common disorders that affect neuromuscular transmission. It is currently one of the most understood and characterised autoimmune disorders Its typical symptoms are fluctuating weakness and fatigue that affects a combination of ocular muscles, bulbar functions, as well as limb and respiratory muscles, which are due to an immune attack against the postsynaptic membrane of the neuromuscular junction. The diagnosis of myasthenia gravis is based on clinical and serological test. It is a disease that can be effectively controlled with the current therapeutic lines, even achieving a complete remission. An update of this interesting disorder is now presented.
